Skin Hypopigmentation Panel

The Skin Hypopigmentation Panel analyzes genes that are associated with hypopigmentation, which is characterized by decreased skin, hair, and/or eye pigmentation. These genes were selected based on the available evidence to date to provide a broad analysis for inherited hypopigmentation. The genetic heterogeneity associated with these conditions can make it difficult to use phenotype as the sole criterion to select a definitive cause. Broad panel testing allows for an efficient evaluation of several potential genes based on a single clinical indication. Genetic testing of these genes may confirm a diagnosis and help guide treatment and management decisions. Identification of a disease-causing variant can inform recurrence-risk assessment and genetic counseling.