Platelet Disorders Panel

The Platelet Disorders Panel analyzes genes associated with disorders of platelet number or function. These disorders are typically characterized by bleeding symptoms which may include excessive bruising, purpura, excessive bleeding after surgery or trauma, nosebleeds, superficial bleeding into the skin (petechiae), and menorrhagia in women. Given the clinical overlap between these conditions, comprehensive testing enables a more efficient evaluation of multiple conditions based on a single indication for testing. This test may establish a genetic diagnosis, which would eliminate the need for serial gene testing. A genetic diagnosis may guide medical management, enabling a clinician to determine the need for additional evaluations, screenings, and procedures. The GP1BB gene is not offered on this panel. In addition, sequencing for the GP1BA gene is limited to 11 variants.